Generic Name: metformin and rosiglitazone (met FOR min and row zi GLI ta zone)
Brand name: Avandamet
Metformin and rosiglitazone is a combination of two oral diabetes medicines that help control blood sugar levels. The metformin in this combination medication can rarely cause a condition called lactic acidosis, which can be fatal. Seek immediate medical attention if you develop any of the following symptoms of lactic acidosis: unusual tiredness (fatigue) or severe drowsiness, cold skin, muscle pain, breathing trouble or rapid breathing, unusually slow or irregular heartbeat.
Do not use metformin and rosiglitazone if you have kidney disease, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin). Tell your doctor or pharmacist if you are pregnant, planning to become pregnant, or are breast-feeding. This medication works by helping to restore your body's proper response to the insulin you naturally produce.